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Regulatory Protein Collection

"Unraveling the Intricacies of Regulatory Proteins: A Dance with DNA" In the intricate world of gene regulation

Background imageRegulatory Protein Collection: Zinc fingers bound to a DNA strand

Zinc fingers bound to a DNA strand, molecular model. The double helix of DNA (deoxyribonucleic acid, red and yellow) is seen here with two Zif268 proteins (blue and green)

Background imageRegulatory Protein Collection: Sir3 gene silencer acting on DNA F006 / 9730

Sir3 gene silencer acting on DNA F006 / 9730
Sir3 gene silencer acting on DNA, molecular model. Sir3 (light blue) is acting on a circular strand of DNA (deoxyribonucleic acid, pink)

Background imageRegulatory Protein Collection: Gene activator protein F006 / 9406

Gene activator protein F006 / 9406
Gene activator protein. Molecular model of catabolite gene activator protein (CAP, yellow) complexed with deoxyribonucleic acid (DNA, red and blue) and RNA polymerase (green and pink)

Background imageRegulatory Protein Collection: Gene activator protein F006 / 9269

Gene activator protein F006 / 9269
Gene activator protein. Molecular model of catabolite gene activator protein (CAP, pink and green) bound to a molecule of deoxyribonucleic acid (DNA, across top)

Background imageRegulatory Protein Collection: Zinc finger bound to DNA

Zinc finger bound to DNA. Molecular model showing a zinc finger molecule bound (orange) to a strand of DNA (deoxyribonucleic acid, pink and green)

Background imageRegulatory Protein Collection: Zinc finger bound to DNA C014 / 0864

Zinc finger bound to DNA C014 / 0864
Zinc finger bound to DNA. Molecular model showing a zinc finger molecule bound to a strand of DNA (deoxyribonucleic acid)

Background imageRegulatory Protein Collection: Sir3 gene silencer acting on DNA C015 / 7062

Sir3 gene silencer acting on DNA C015 / 7062
Sir3 gene silencer acting on DNA, molecular model. Sir3 (purple and grey) is acting on a circular strand of DNA (deoxyribonucleic acid, red)

Background imageRegulatory Protein Collection: Sir3 gene silencer acting on DNA C015 / 7061

Sir3 gene silencer acting on DNA C015 / 7061
Sir3 gene silencer acting on DNA

Background imageRegulatory Protein Collection: Sir3 gene silencer acting on DNA C016 / 2325

Sir3 gene silencer acting on DNA C016 / 2325
Sir3 gene silencer acting on DNA, molecular model. Sir3 (bright green) is acting on a circular strand of DNA (deoxyribonucleic acid, red and yellow)

Background imageRegulatory Protein Collection: Sir3 gene silencer acting on DNA C016 / 2324

Sir3 gene silencer acting on DNA C016 / 2324
Sir3 gene silencer acting on DNA, molecular model. Sir3 (light blue) is acting on a circular strand of DNA (deoxyribonucleic acid, pink)

Background imageRegulatory Protein Collection: Zinc finger-RNA complex

Zinc finger-RNA complex. Computer models of zinc finger protein molecules complexed with RNA (ribonucleic acid) molecules

Background imageRegulatory Protein Collection: Gene activator protein

Gene activator protein. Computer artwork of catabolite gene activator protein (CAP, blue and red) bound to a molecule of deoxyribonucleic acid (DNA)


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"Unraveling the Intricacies of Regulatory Proteins: A Dance with DNA" In the intricate world of gene regulation, regulatory proteins play a vital role in orchestrating the delicate balance between activation and silencing. One such group of proteins, known as zinc fingers, exhibit an uncanny ability to bind to specific regions on a DNA strand like skilled dancers finding their perfect partners. Among them is Sir3, a gene silencer that exerts its influence on DNA F006 / 9730. With finesse and precision, it delicately wraps around the DNA strand, effectively muting the expression of targeted genes. In contrast, gene activator proteins F006 / 9406 and F006 / 9269 take center stage as they interact with their respective target sequences. Their arrival sparks a cascade of events that lead to enhanced gene expression and cellular activity. The dance continues as more zinc fingers gracefully embrace different sections of the DNA helix. Each interaction holds immense significance; for instance, Zinc finger bound to DNA C014 / 0864 guides specific genetic instructions crucial for cellular processes. As our understanding deepens, we witness yet another captivating performance by gene activator proteins - masters at unlocking genetic potential. Their presence triggers a symphony within cells as they activate key genes responsible for growth and development. Returning to zinc fingers once again entwined with their partner strands - this time binding tightly to regulate Sir3's actions on DNA C015 / 7062 and C015 / 7061 or even C016 /2325. These interactions reveal how these silent guardians maintain order within our genome by preventing unwanted gene expression. Through this intricate choreography between regulatory proteins and DNA strands emerges an awe-inspiring narrative - one where each step determines whether certain genes remain dormant or awaken into action. Understanding these molecular dances sheds light on fundamental biological processes while offering promising avenues for future research in medicine and biotechnology.