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Caspase 1 molecule

Caspase 1 molecule


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Caspase 1 molecule

Caspase-1 molecule. Computer artwork showing the secondary structure of a molecule of caspase-1. Caspase-1 is a protease, an enzyme that cleaves proteins. It is found predominantly in the cell cytoplasm, where it activates interleukin-1-beta, a molecule that mediates immune and inflammatory responses. Due to this activity caspase-1 is also known as ICE (interleukin-1-beta converting enzyme). Like other caspases it also plays a role in apoptosis (programmed cell death), but only when over-expressed

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6294453

© DR MARK J. WINTER/SCIENCE PHOTO LIBRARY

Apoptosis Compound Compounds Enzyme Enzymes Helices Heterodimer Heterodimeric Immune Response Inflammatory Response Molecules Programmed Cell Death Protease Secondary Structure Sheets Sub Unit Subunits Bio Chemistry Molecular Protein


EDITORS COMMENTS
This print showcases the intricate structure of a Caspase-1 molecule, depicted through stunning computer artwork. Caspase-1 is an essential protease enzyme responsible for cleaving proteins within the cell cytoplasm. Its primary function lies in activating interleukin-1-beta, a crucial molecule involved in mediating immune and inflammatory responses. Also known as ICE (interleukin-1-beta converting enzyme), caspase-1's activity extends beyond its role in immune response regulation. It plays a significant part in apoptosis, or programmed cell death, but only when present in excessive amounts. The illustration beautifully captures the complexity of this biological compound with its helices and sheets forming a mesmerizing secondary structure. The heterodimeric subunit arrangement of caspase-1 is highlighted, emphasizing its functional importance. As a cysteine protease containing both cysteine and aspartic acid residues, it acts as an executioner protein during programmed cell death processes. Science Photo Library has expertly captured the essence of this molecular marvel through their artful representation. This print serves as a testament to the fascinating world of biology and chemistry intersecting at the molecular level. It offers viewers an opportunity to appreciate the beauty hidden within these compounds that drive vital cellular processes such as inflammation regulation and controlled cell death – all encapsulated within this single captivating image.

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