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Nanopore DNA sequencing, conceptual image C013 / 8901
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Nanopore DNA sequencing, conceptual image C013 / 8901
Nanopore DNA sequencing, conceptual image. Computer artwork of a DNA (deoxyribonucleic acid) strand (green and red) being sequenced (letters) as it passes through a nanopore (tiny hole) in a graphene sheet (mesh). Graphene is a single layer of graphite composed of hexagonally arranged carbon atoms. Nanopore sequencing involves pulling a DNA strand through a tiny hole in a graphene membrane suspended in a salt solution with a voltage applied across it. Ions moving from one side of the membrane to the other create an electric current. As each of four different DNA bases (letters) passes through the pore, the current strength decreases to a different extent, making it possible to rapidly sequence the bases
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Media ID 9200501
© RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY
Base Bases Carbon Conductor Current Electric Current Electrical Electricity Flat Fullerene Gene Genes Genetic Graphene Graphite Hexagonal Hole Layer Letters Membrane Nano Nano Fence Nano Graph Nanotechnology Organic Planar Sequence Sequenced Sheet Strand Voltage Biochemical Biochemistry Concepts Deoxyribonucleic Acid Genetics Molecular Model Passing Through
EDITORS COMMENTS
This print showcases the cutting-edge technology of nanopore DNA sequencing. In this conceptual image, we are presented with a computer artwork representation of the process. A DNA strand, depicted in vibrant green and red colors, is seen passing through a minuscule hole known as a nanopore within a graphene sheet. Graphene, an ultra-thin layer composed of carbon atoms arranged in hexagonal patterns, acts as a conductive mesh for this revolutionary sequencing technique. The membrane containing the graphene is suspended in a salt solution while being subjected to an applied voltage. As the DNA strand traverses through the nanopore, ions move across the membrane from one side to another, generating an electric current. The true marvel lies in how each of the four different DNA bases (represented by letters) affects the strength of this electric current differently as they pass through the pore. This unique characteristic enables rapid and accurate sequencing of these genetic building blocks. With its implications reaching far into genetics and biochemistry realms, nanopore sequencing represents a significant breakthrough in molecular analysis. By combining nanotechnology and biochemical principles, scientists can unravel intricate genetic codes at an unprecedented pace. Ramon Andrade's masterful illustration captures both the scientific complexity and aesthetic beauty inherent in this groundbreaking technological advancement. It serves as a testament to human ingenuity and our relentless pursuit of understanding life's fundamental blueprint - DNA.
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