Trimethoprim molecule

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Trimethoprim molecule

Trimethoprim. Computer-generated molecular model of trimethoprim (molecular formula: C14.H18.N4.O3), an antibiotic used to treat urinary tract infections. It is composed of carbon (yellow), hydrogen (white), nitrogen (green) and oxygen (blue). Trimethoprim works by inhibiting the synthesis of folic acid (folate) inside the bacterial cell. Folic acid is necessary for the production of genetic material (deoxyribonucleic acid, DNA). Without DNA, the bacteria cannot reproduce and the infection is stopped (bacteriostatic effect). Trimethoprims efficiency is being affected by the increase in bacterial resistance

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6280621

© DR TIM EVANS/SCIENCE PHOTO LIBRARY

Anti Biotic Antibacterial Bacteriology Bacteriostatic Pharmacological Pharmacology Resistance Resistant Structural Computer Artwork Ineffective Micro Biology Microbiological Molecular

EDITORS COMMENTS
This print showcases a computer-generated molecular model of the Trimethoprim molecule, an essential antibiotic used to combat urinary tract infections. The intricate structure is composed of carbon, hydrogen, nitrogen, and oxygen atoms represented by vibrant yellow, white, green, and blue colors respectively. Trimethoprim's remarkable efficacy lies in its ability to hinder the synthesis of folic acid within bacterial cells. Folic acid plays a crucial role in DNA production - the genetic material necessary for bacterial reproduction. By obstructing this process, Trimethoprim effectively halts bacterial growth and prevents further infection (known as bacteriostatic effect). However, this image also serves as a reminder that the effectiveness of Trimethoprim is being compromised due to increasing bacterial resistance. As bacteria evolve over time and develop mechanisms to counteract antibiotics like Trimethoprim, their ability to resist treatment becomes more prevalent. Through this visually stunning representation created with advanced computer artwork techniques from Science Photo Library's collection on microbiology and pharmacology subjects; we gain insight into both the structural complexity of this important antibacterial agent and the challenges faced by medical professionals in combating resistant strains.

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