Vaccinia viruses, TEM
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Vaccinia viruses, TEM
Vaccinia virus particles. Coloured transmission electron micrograph (TEM) of sectioned vaccinia virus particles. The genetic cores (red) are covered by membrane layers (green) taken from the host cell that replicated the virus. Vaccinia belongs to the orthopoxvirus group. Formation of new virus particles occurs in the cytoplasm of the host cell, whereas most other viruses replicate in the cell nucleus. The vaccinia virus causes cowpox, a disease of cattle and humans, which produces skin lesions. It was first used by Edward Jenner in 1796 to protect (vaccinate) against smallpox, a related and far more deadly human disease
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6412552
© DR KLAUS BOLLER/SCIENCE PHOTO LIBRARY
Cowpox False Colour Micro Organism Microbe Orthopoxvirus Particle Particles Pathogens Pathological Pathology Small Pox Transmission Electron Micrograph Transmission Electron Microscope Vaccination Vaccine Vaccinia Viral Virion Virions Virology Viruses False Coloured Micro Biology Microbiological Pathogen Section Sectioned Virus
EDITORS COMMENTS
This print showcases the intricate structure of Vaccinia viruses, as captured through a transmission electron microscope (TEM). The false-colored image reveals sectioned vaccinia virus particles, with their genetic cores depicted in vivid red and membrane layers derived from the host cell shown in vibrant green. Belonging to the orthopoxvirus group, Vaccinia is unique in its replication process, which takes place within the cytoplasm of the host cell rather than the nucleus. The significance of this virus lies not only in its ability to cause cowpox, a disease affecting both cattle and humans that manifests as skin lesions but also in its historical role. Edward Jenner famously utilized Vaccinia virus back in 1796 for smallpox vaccination. Smallpox was an immensely deadly human disease at that time, making Jenner's pioneering use of Vaccinia a breakthrough moment for medicine. This visually striking image provides valuable insights into virology and pathology by highlighting key features of these viral particles. It serves as a reminder of how scientific advancements have enabled us to understand and combat dangerous pathogens like Vaccinia through vaccines. This photograph is part of Science Photo Library's extensive collection on microbiology and offers an intriguing glimpse into the microscopic world where viruses interact with their hosts.
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