Citric Acid Cycle Collection

Metabolic enzyme, artwork
Metabolic enzyme. Computer artwork of aconitase (blue), in complex with ferritin messenger ribonucleic acid (mRNA, red). Aconitase is involved in the citric acid cycle but here it is performing a

Succinyl-CoA synthetase enzyme F006 / 9592
Succinyl-CoA synthetase bound to GTP, molecular model. Also known as succinyl coenzyme A synthetase (SCS), this enzyme catalyses the reversible reaction between succinyl-CoA and succinic acid

Citrate acid cycle enzyme F006 / 9305
Citrate acid cycle enzyme. Molecular model of the enzyme dihydrolipoamide succinyltransferase. This enzyme is involved in the citric acid (or Krebs) cycle

Pyruvate dehydrogenase complex C018 / 9192
Pyruvate dehydrogenase complex, 3D model. This enzyme complex is responsible for the step that links glycolysis to the citric acid (Krebs) cycle

NADP-dependent isocitrate dehydrogenase F006 / 9778
NADP-dependent isocitrate dehydrogenase, molecular model. This enzyme catalyses the third step in the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

Metabolic enzyme molecule F006 / 9770
Metabolic enzyme. Molecular model of the enzyme aconitase with isocitrate bound. Aconitase is involved in the citric acid (or Krebs) cycle

Isocitrate dehydrogenase kinase F006 / 9698
Isocitrate dehydrogenase kinase. Molecular model of isocitrate dehydrogenase kinase phosphatase (AceK) complexed with its substrate isocitrate dehydrogenase (ICDH)

Isocitrate dehydrogenase molecule F006 / 9663
Isocitrate dehydrogenase, molecular model. This enzyme catalyses the third step in the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

Citrate synthase molecule F006 / 9573
Citrate synthase, molecular model. This enzyme is involved in the first step of the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

Citrate synthase molecule F006 / 9443
Citrate synthase, molecular model. This enzyme is involved in the first step of the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

Succinate dehydrogenase enzyme F006 / 9432
Succinate dehydrogenase enzyme. Molecular model of the succinate dehydrogenase (complex II) enzyme from an Escherichia coli bacterium

Pyruvate dehydrogenase complex enzyme F006 / 9303
Pyruvate dehydrogenase complex enzyme. Molecular model of dihydrolipoyl transacetylase one of the enzymes in the pyruvate dehydrogenase complex

Citrate synthase molecule F006 / 9277
Citrate synthase, molecular model. This enzyme is involved in the first step of the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

Metabolic enzyme molecule F006 / 9262
Metabolic enzyme. Molecular model of the enzyme aconitase, which is involved in the citric acid (or Krebs) cycle. The citric acid cycle is the process by which mitochondria convert glucose to energy

Metabolic enzyme molecule F006 / 9227
Metabolic enzyme. Molecular model of the enzyme aconitase, which is involved in the citric acid (or Krebs) cycle. The citric acid cycle is the process by which mitochondria convert glucose to energy

Citrate synthase molecule C015 / 6694
Citrate synthase, molecular model. This enzyme is involved in the first step of the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

Citrate synthase molecule C015 / 6693
Citrate synthase, molecular model. This enzyme is involved in the first step of the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

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The citric acid cycle, also known as the Krebs cycle or tricarboxylic acid cycle, is a fundamental metabolic pathway that plays a crucial role in energy production within our cells. This intricate process involves several key enzymes and molecules that work together to convert nutrients into usable energy. One of these essential enzymes is succinyl-CoA synthetase (F006/9592), which catalyzes the conversion of succinyl-CoA to succinate, generating ATP in the process. Another vital enzyme is citrate synthase (F006/9573 and F006/9443), responsible for combining acetyl-CoA with oxaloacetate to form citrate. The pyruvate dehydrogenase complex (C018/9192 and F006/9303) also plays a significant role by converting pyruvate into acetyl-CoA, which then enters the citric acid cycle. Additionally, NADP-dependent isocitrate dehydrogenase (F006/9778) helps regulate this cycle by catalyzing the conversion of isocitrate to alpha-ketoglutarate while producing NADPH. Isocitrate dehydrogenase kinase (F006/9698) controls the activity of another critical enzyme called isocitrate dehydrogenase (F006/9663). This enzyme converts isocitrate into alpha-ketoglutarate as part of the overall cycle. Lastly, we have succinate dehydrogenase (F006/9432), an enzyme embedded in the inner mitochondrial membrane that oxidizes succinate to fumarate while transferring electrons to coenzyme Q10. This step connects the citric acid cycle with oxidative phosphorylation, contributing further to ATP synthesis. As fascinating as it may sound scientifically, this caption aims not only at highlighting these metabolic enzymes but also appreciating their beauty as artwork.