Thalidomide drug molecule

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Thalidomide drug molecule

Thalidomide (C13.H10.N2.O4) molecular model. The atoms are colour-coded: carbon (yellow), hydrogen (white), nitrogen (blue) and oxygen (red). This is S-thalidomide, a mirror image (enantiomer) of R- thalidomide, both of which share the same structural formula. Thalidomide was developed as a sedative drug to aid sleep in pregnant woman. It was found to cause foetal abnormalities (stunted limbs, or phocomelia), and was withdrawn in 1961. Further research discovered that only the " S" form caused deformities. A purified drug containing only the " R" enantiomer is now being used to treat leprosy and as an anti-cancer drug. See A624/159 for an image of R-thalidomide

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Media ID 6279669

© DR TIM EVANS/SCIENCE PHOTO LIBRARY

Antineoplastic Atomic Atoms Compound Compounds Drug Enantiomer Hypnotic Leprosy Molecules Pharmaceutical Pharmaceutics Pregnancy Sedative Sleeping Structural Teratogen Thalidomide Bio Chemistry Biochemical Complications Molecular

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