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Images Dated 8th September 1985

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TEM of plasmids of bacterial DNA fron E. coli Featured 8 Sep 1985 Image

TEM of plasmids of bacterial DNA fron E. coli

False-colour transmission electron micrograph of plasmids (PBR 322) of bacterial DNA from the bacterium Escherichia coli (E. coli). A plasmid is a molecule of DNA that can exist apart from the chromosome in a bacterium, & which can replicate on its own. This plasmid, designated PBR 322, is the one most commonly used in genetic engineering work. Foreign DNA is spliced to it & the composite or "chimeric" plasmid is then introduced into an Escherichia coli bacterium where it propagates & expresses the genetic information carried by the transplanted DNA. Magnification: X 18, 450 (at 35mm size) X153, 000 (at 10x8 size)