Insulin receptor substrate 1 molecule
Wall Art and Photo Gifts from Science Photo Library
Insulin receptor substrate 1 molecule
Insulin receptor substrate 1. Molecular model of the secondary structure of the protein insulin receptor substrate 1 (IRS1), bound to a molecule of phosphotyrosine (ball and stick molecule). This protein is phosphorylated by the insulin receptor, a transmembrane receptor. Phosphorylation of IRS1 leads to an increase in glucose transporter molecules on the membrane of insulin-responsive tissues, such as muscle and adipose (fat) tissue, and so an increase in glucose uptake. A decrease in the activity of the insulin receptor leads to type 2 diabetes
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6301365
© DR MARK J. WINTER/SCIENCE PHOTO LIBRARY
Alpha Helix Beta Sheet Beta Sheets Bound Compound Compounds Signal Transduction Bio Chemistry Biochemical Molecular Molecular Model Protein
EDITORS COMMENTS
This print showcases the intricate molecular structure of Insulin Receptor Substrate 1 (IRS1) bound to a phosphotyrosine molecule. The secondary structure of IRS1, depicted in this stunning illustration, plays a crucial role in glucose metabolism and insulin signaling. As an essential component of the insulin receptor pathway, IRS1 undergoes phosphorylation by the transmembrane insulin receptor. This process triggers a cascade of events that ultimately leads to an increase in glucose transporter molecules on the surface of insulin-responsive tissues like muscle and adipose tissue. Consequently, these tissues become more efficient at absorbing glucose from the bloodstream. The significance of this molecular interaction becomes even more apparent when considering its implications for type 2 diabetes mellitus. A decrease in activity or dysfunctionality within the insulin receptor can disrupt this delicate balance, resulting in impaired glucose uptake and elevated blood sugar levels characteristic of diabetes. Through its precise depiction, this artwork not only highlights the structural complexity but also emphasizes the critical role played by IRS1 in cellular signal transduction and metabolic regulation. It serves as a reminder that understanding these intricate biochemical processes is vital for unraveling complex diseases such as type 2 diabetes mellitus. This visually striking image captures both artistry and scientific precision while shedding light on one aspect of biology's fascinating world at a molecular level.
MADE IN AUSTRALIA
Safe Shipping with 30 Day Money Back Guarantee
FREE PERSONALISATION*
We are proud to offer a range of customisation features including Personalised Captions, Color Filters and Picture Zoom Tools
SECURE PAYMENTS
We happily accept a wide range of payment options so you can pay for the things you need in the way that is most convenient for you
* Options may vary by product and licensing agreement. Zoomed Pictures can be adjusted in the Cart.