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Angiotensin II, polypeptide hormone

Angiotensin II, polypeptide hormone


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Angiotensin II, polypeptide hormone

Angiotensin II, molecular model. Angiotensin II is a polypeptide hormone that functions in the body to control arterial blood pressure. It is the principle mediator of the renin-angiotensin system (RAS), synthesised from angiotensin I by the angiotensin-converting enzyme ACE. It stimulates vasoconstriction (narrowing of the blood vessels to raise the blood pressure) and the retention of salt and water. The hormone has been found to increase the risk of thrombosis through the adhesion and aggregation of platelets, and has also been put forward as the possible cause of vascular and cardiac muscle hypertrophy (enlargement of the heart). In this model atoms are shown as balls; carbon in yellow, hydrogen in white, nitrogen in blue and oxygen in red

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6280539

© DR MARK J. WINTER/SCIENCE PHOTO LIBRARY

Arteries Blood Pressure Blood Vessels Cardiac Compound Compounds Endocrinology Hormone Mediator Molecules Narrow Narrowing Structural Vascular Vasoconstriction Vasoconstrictor Bio Chemistry Biochemical Molecular Molecular Model


EDITORS COMMENTS
This print showcases the intricate molecular structure of Angiotensin II, a vital polypeptide hormone that plays a crucial role in regulating arterial blood pressure within the human body. Serving as the principal mediator of the renin-angiotensin system (RAS), this hormone is synthesized from angiotensin I by the enzyme ACE. The visually stunning model reveals atoms represented as vibrant balls, with carbon depicted in yellow, hydrogen in white, nitrogen in blue, and oxygen in red. Through its remarkable functionality, Angiotensin II stimulates vasoconstriction - effectively narrowing blood vessels to elevate blood pressure - while also promoting salt and water retention. However, this extraordinary hormone has been associated with potential risks such as thrombosis due to platelet adhesion and aggregation. Furthermore, it has been suggested that Angiotensin II may contribute to vascular and cardiac muscle hypertrophy or enlargement of the heart. With its profound implications for endocrinology and biochemistry research, this artwork not only captures the structural complexity of this compound but also serves as a reminder of how molecules like Angiotensin II shape our physiological processes. Science Photo Library's expertise shines through once again with their exceptional portrayal of this essential polypeptide hormone.

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