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Skin pigmentation in Addisons disease
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Skin pigmentation in Addisons disease
Skin pigmentation from Addisons disease. Light micrograph of a section through the skin of a patient with Addisons disease. Also called hypocortisolism, Addisons is a hormonal disorder where the adrenal glands do not produce sufficient quantities of steroid hormones. One of the primary symptoms is hyperpigmentation of the skin, where the colour of the skin darkens in areas that are not exposed to the sun, for example the palms of the hands and nipples. Here, the excess pigment is seen as dark spots where the epithelial skin layer (pink) meets the underlying layer (yellow). Other symptoms include vitiligo (patches of lightened skin), low blood pressure, low blood sugar, fainting, vomiting and convulsions. Treatment is with hormone therapy
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6413178
© STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY
Adrenal Gland Darkened Endocrine Endocrinology Excess Excessive Histopathological Histopathology Hormonal Hormones Pigmentation Shortage Skin Slice Sliced Abnormal Condition Darkening Darker Disorder Health Care Imbalance Light Micrograph Light Microscope Malfunction Section Sectioned Unhealthy
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This print from Science Photo Library showcases the skin pigmentation in Addisons disease, a hormonal disorder characterized by insufficient production of steroid hormones in the adrenal glands. The image, taken under a light microscope, reveals a section through the skin of an affected patient. One of the prominent symptoms of Addisons disease is hyperpigmentation, where areas not exposed to sunlight darken. In this micrograph, we can observe dark spots where the epithelial skin layer meets the underlying layer due to excess pigment accumulation. This abnormal darkening contrasts with the pink color of the epithelium and yellow hue of the underlying tissue. Addisons disease also presents other distressing symptoms such as vitiligo (patches of lightened skin), low blood pressure, low blood sugar levels, fainting episodes, vomiting tendencies, and convulsions. To manage this condition effectively, hormone therapy is administered to address hormonal imbalances caused by adrenal insufficiency. The intricate details captured in this histopathological image shed light on both medical professionals and individuals seeking knowledge about Addisons disease. It serves as a valuable resource for understanding how this disorder affects pigmentation within our bodies' largest organ - our skin.
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