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Human prion protein, molecular model F006 / 9477
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Human prion protein, molecular model F006 / 9477
Human prion protein, molecular model. Prions are abnormal proteins that cause a group of fatal neurodegenerative diseases including BSE in cows and CJD in humans. Prions do not have a nucleic acid (RNA or DNA) genome for replication. Abnormal infectious prions directly change normal prions found in the brain to the abnormal form. The altered prion structure is extremely stable and accumulates as amyloid plaques that lead to neurodegeneration
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9255239
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Alpha Helix Amyloid Plaque Beta Sheet Encephalopathies Illness Infection Infectious Neurodegeneration Neurodegenerative Prion Proteomics Strand Tertiary Structure Biochemical Biochemistry Cutouts Disorder Molecular Molecular Model Molecular Structure Neurological Protein Scrapie
EDITORS COMMENTS
This print showcases the intricate molecular model of the Human Prion Protein, shedding light on the devastating impact of prions on our health. Prions, abnormal proteins devoid of a nucleic acid genome, are responsible for triggering fatal neurodegenerative diseases such as BSE in cows and CJD in humans. The absence of RNA or DNA makes their replication process distinct from other infectious agents. The image vividly captures how abnormal infectious prions directly alter normal prions found in the brain, leading to a cascade effect that results in an accumulation of amyloid plaques. These stable altered structures become detrimental to neurological function and ultimately cause neurodegeneration. Against a clean white background, this illustration serves as a powerful reminder of the complex interplay between biology and disease. It highlights ongoing research efforts aimed at understanding these disorders at a molecular level and developing potential treatments. With its detailed portrayal of alpha helices, beta sheets, tertiary structures, and molecular strands, this artwork provides valuable insights into the mechanisms underlying conditions like CJD and BSE. Its scientific significance extends beyond mere aesthetics; it represents progress towards unraveling mysteries within proteomics and biochemistry. As we delve deeper into deciphering these enigmatic illnesses plaguing humanity's central nervous system (CNS), this image stands as both an educational tool for healthcare professionals and a testament to our unwavering commitment to combating neurodegenerative diseases.
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