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Kinase molecule, secondary structure

Kinase molecule, secondary structure


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Kinase molecule, secondary structure

Kinase molecule, computer model. Kinases are enzymes that catalyse the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP or ADP) to a substrate (such as a protein or lipid). This process is known as phosphorylation. The largest group of kinases are protein kinases. Up to 518 different types have been identified in humans and are used to transmit signals and control complex processes in cells. In this model the molecules shape (secondary structure) is seen, comprising alpha helices (coils), beta sheets (arrows) and linking regions (lines). Also seen is a molecule of the inhibitor 5-bromo-indirubin (centre right). Protein kinase inhibitors are a type of enzyme inhibitor that specifically block the action of a protein kinase

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6295167

© DR TIM EVANS/SCIENCE PHOTO LIBRARY

Acids Alpha Helix Amino Acid Arrow Arrows Beta Sheet Block Blocked Blocks Coil Coils Complex Composition Compound Compounds Enzyme Enzymes Helices Inhibitor Kinase Macromolecule Molecules Pharmacological Pharmacology Phosphorylation Secondary Structure Shape Sheets Bio Chemistry Biochemical Molecular Molecular Model Protein


EDITORS COMMENTS
This print showcases a computer model of a kinase molecule, highlighting its intricate secondary structure. Kinases are remarkable enzymes that play a crucial role in catalyzing the transfer of phosphate groups from high-energy molecules like ATP or ADP to substrates such as proteins or lipids. This process, known as phosphorylation, is essential for transmitting signals and controlling complex cellular processes. The image provides an artistic representation of the kinase's molecular composition, revealing alpha helices (coils), beta sheets (arrows), and linking regions (lines). Additionally, we can observe a molecule of the inhibitor 5-bromo-indirubin positioned at the center-right section. Protein kinase inhibitors like this one have the unique ability to block the action of protein kinases specifically. With over 500 different types identified in humans alone, protein kinases hold immense significance in biology and medicine. They serve as vital components in biochemical pathways and regulate various physiological functions within cells. This visually stunning artwork beautifully captures both the complexity and elegance of these macromolecules. It serves as a reminder of how scientific advancements continue to unravel nature's intricacies at a molecular level while offering potential insights into pharmacology and medical research.

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