Macrophage and tuberculosis vaccine, TEM
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Macrophage and tuberculosis vaccine, TEM
Macrophage and tuberculosis vaccine. Coloured transmission electron micrograph (TEM) of phagocytosed (engulfed) Mycobacterium bovis bacteria (purple) in a macrophage (green) white blood cell. The cell nucleus (yellow) is also seen. This is the BCG (bacillus of Calmette- Guerin) strain of the bacteria, used in the vaccination for tuberculosis (TB). The bacteria is live but attenuated (weakened). The macrophage destroys the bacteria. The vaccine primes the immune system, without causing disease, so that it responds more rapidly if infected with TB bacteria
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6421296
© SCIENCE PHOTO LIBRARY
Attenuated Bacillus Of Calmette Guerin Bacteria Bacteriology Bacterium Destroying Engulfed Engulfing Immune Immune System Immunology Live Macrophage Mycobacterium Bovis Phagocytosing Phagocytosis Response Strain System Transmission Electron Micrograph Transmission Electron Microscope Tuberculosis Vaccination Vaccine Weakened White Blood Cell Cells False Coloured Micro Biology Microbiological
EDITORS COMMENTS
This print showcases the intricate relationship between a macrophage and the tuberculosis vaccine. Through the lens of a transmission electron microscope (TEM), we are granted an up-close view of this remarkable process. The purple-colored Mycobacterium bovis bacteria, belonging to the BCG strain, can be seen engulfed within a green macrophage, which is a type of white blood cell responsible for defending our bodies against foreign invaders. The yellow nucleus of the cell stands out amidst this microscopic battlefield, highlighting its vital role in orchestrating immune responses. This particular strain of bacteria has been attenuated or weakened to prevent disease but still elicits a response from our immune system. As depicted here, the macrophage diligently destroys these intruders while simultaneously priming our body's defense mechanisms. This image not only offers insight into microbiological processes but also serves as a visual representation of medical advancements in vaccination against tuberculosis. By stimulating our immune system without causing harm, this vaccine ensures that if ever infected with TB bacteria, our body will respond swiftly and effectively. Science Photo Library continues to provide us with awe-inspiring visuals that bridge the gap between science and artistry.
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