Type I topoisomerase bound to DNA C014 / 0862

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Type I topoisomerase bound to DNA C014 / 0862

Type I topoisomerase bound to DNA. Molecular model showing a type I topoisomerase molecule (khaki) bound to a strand of DNA (deoxyribonucleic acid, pink and green). The topoisomerase enzymes assist in uncoiling DNA. DNA is usually stored in a supercoiled form, which must be unravelled before it can be replicated or translated into proteins. Type I topoisomerase changes the linkage in multiples of one, while Type II changes the linkages in steps of two

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 9227759

© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Bound Complex Complexed Double Helix Genetic Molecules Mycological Mycology Nucleic Acid Proteins Proteomics Spacefill Spacefilled Unravelling Biochemical Biochemistry Cutouts Deoxyribonucleic Acid Genetics Molecular Model Protein

EDITORS COMMENTS
This print showcases the intricate relationship between Type I topoisomerase and DNA. The molecular model depicted here beautifully illustrates the binding of a khaki-colored Type I topoisomerase molecule to a strand of DNA, represented by shades of pink and green. In the world of biology, these topoisomerase enzymes play a crucial role in uncoiling DNA strands. DNA is typically stored in a supercoiled form, tightly wound like a spring. However, before it can undergo replication or translation into proteins, this coiled structure must be unraveled. This is where Type I topoisomerase comes into play - it changes the linkages in multiples of one, effectively relieving tension within the DNA helix. The significance of this interaction lies in its impact on genetic processes. By altering the linkage pattern between nucleotides within DNA molecules, Type I topoisomerase facilitates essential biological functions such as gene expression and repair. LAGUNA DESIGN/SCIENCE PHOTO LIBRARY's artwork not only captures the complexity of this biochemical process but also highlights its importance for our understanding of genetics and protein synthesis. With its clean white background and meticulous attention to detail, this illustration serves as an invaluable resource for scientists studying molecular biology or anyone fascinated by the wonders hidden within our genetic code.

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